Written by: Paul W.S. Anderson
Milla Jovovich: Alice
Michelle Rodriguez: Rain Ocampo
Eric Mabius: Matthew Addison
James Purefoy: Spence Parks
Martin Crewes: Chad Kaplan
Colin Salmon: James “One” Shade
Ryan McCluskey: Mr Grey
Oscar Pearce: Mr. Red
Indra Ové: Ms. Black
Anna Bolt: Dr. Green
Joseph May: Dr. Blue
Robert Tannion: Dr. Brown
Heike Makatsch: Lisa Addison
Jaymes Butler: Clarence the Security Guard
Stephen Billington: Mr. White
Fiona Glascott: Ms. Gold
Pasquales Aleardi: J.D. Salinas
Liz May Brice: Medic
Torsten Jerabek: Commando #1
Marc Logan-Black: Commando #2
Michaela Dicker: Red Queen
Jeremy Bolt: Zombie