Written by: Paul W.S. Anderson

Milla Jovovich: Alice

Michelle Rodriguez: Rain Ocampo

Eric Mabius: Matthew Addison

James Purefoy: Spence Parks

Martin Crewes: Chad Kaplan

Colin Salmon: James “One” Shade

Ryan McCluskey: Mr Grey

Oscar Pearce: Mr. Red

Indra Ové: Ms. Black

Anna Bolt: Dr. Green

Joseph May: Dr. Blue

Robert Tannion: Dr. Brown

Heike Makatsch: Lisa Addison

Jaymes Butler: Clarence the Security Guard

Stephen Billington: Mr. White

Fiona Glascott: Ms. Gold

Pasquales Aleardi: J.D. Salinas

Liz May Brice: Medic

Torsten Jerabek: Commando #1

Marc Logan-Black: Commando #2

Michaela Dicker: Red Queen

Jeremy Bolt: Zombie